Burdock is considered to be safe to eat, but you should only buy it from reputable sellers and should never collect it in the wild. The Burdock plant resembles and is in the same plant family as belladonna nightshade plants, which are highly toxic. They often grow together. If you’re taking burdock supplements, take small doses only in moderation. More research is needed to determine the safety of the supplement. Burdock root is a natural diuretic, so you shouldn’t take it if you’re dehydrated. You also shouldn’t take it if you’re also taking other diuretics or water pills, as it can increase dehydration. If you’re allergic to chrysanthemums or daisies, you may be at an increased risk of having an allergic reaction to burdock root and should avoid it. Pregnant women or women trying to become pregnant shouldn’t take burdock root or supplements.